Prevalence and associated factors of metabolic syndrome among Omani adults with mental illnesses: a cross-sectional study
Individuals with mental illnesses are at increased risk of developing metabolic syndrome (MetS), a
cluster of cardiovascular and metabolic abnormalities. Despite growing evidence globally, there is a
lack of research in the Gulf region, particularly in Oman. This study is the first to assess the prevalence
and associated factors of MetS among Omani adults with mental illnesses. A descriptive cross-sectional
design was employed. Three diagnostic criteria were used to assess MetS: the International Diabetes
Federation (IDF) criteria, the modified Adult Treatment Panel III (ATP III), and the Joint Statement
of the IDF Task Force with other organizations, aiming to enhance comparability and diagnostic
consistency. A convenience sample of 251 Omani adults with mental illnesses was recruited from the
outpatient departments of two tertiary hospitals in Muscat, Sultanate of Oman. Metabolic syndrome
prevalence was 29.9%, 30.3%, and 33.1% according to the ATP III-A, IDF, and Joint Statement criteria,
respectively. Logistic regression analysis showed that greater waist circumference (OR = 1.06, 95%
CI: 1.03?1.09, p < 0.001) and higher triglyceride levels (OR = 2.43, 95% CI: 1.40?4.22, p = 0.002) were
significantly associated with increased odds of MetS. Higher physical activity (OR = 0.97, 95% CI: 0.95?
0.99, p = 0.031) and the use of antidiabetic medication (OR = 0.17, 95% CI: 0.04?0.73, p = 0.017) were
associated with lower odds. Our findings indicate substantial metabolic risk among Omani adults with
mental illnesses. Accordingly, two concrete service actions are warranted: embed routine metabolic
screening within psychiatric outpatient care; and implement structured lifestyle-support programs
prioritizing physical-activity counselling and weight-management/nutrition referral pathways. These
steps align directly with the study?s observed risk profile.